STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (747 aa)    
Predicted Functional Partners:
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.993
NRP2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.679
KCNMB1
Potassium calcium-activated channel subfamily M regulatory beta subunit 1.
      
 0.669
PLXNC1
Plexin C1.
    
 0.649
PLXND1
Plexin D1.
    
 0.648
SALL4
Spalt like transcription factor 4.
      
 0.642
MST1R
Macrophage stimulating 1 receptor.
    
 0.628
TGM3
TGc domain-containing protein.
      
 0.619
PDCD5
Programmed cell death 5.
      
 0.618
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.615
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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