STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM23ADAM metallopeptidase domain 23. (823 aa)    
Predicted Functional Partners:
LGI2
Leucine rich repeat LGI family member 2.
     
 0.837
LGI3
Leucine rich repeat LGI family member 3.
   
 
 0.674
ADAM22
ADAM metallopeptidase domain 22.
  
 
0.662
LGI4
Leucine rich repeat LGI family member 4.
     
 0.618
MLF1
Myeloid leukemia factor 1.
   
  
 0.521
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.497
LGI1
Leucine rich glioma inactivated 1.
     
 0.492
ADAM11
ADAM metallopeptidase domain 11.
    
0.486
KANSL3
KAT8 regulatory NSL complex subunit 3.
      
 0.455
PRDM5
Zinc finger protein.
      
 0.443
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.