STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLE3DNA polymerase epsilon 3, accessory subunit. (96 aa)    
Predicted Functional Partners:
POLE2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
 0.999
POLE
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.999
G3T912_LOXAF
Histone domain-containing protein.
    
 0.998
CHRAC1
Chromatin accessibility complex subunit 1.
    
 0.986
POLA1
DNA polymerase.
   
 0.959
BAZ1A
Bromodomain adjacent to zinc finger domain 1A.
    
 
 0.953
WRN
WRN RecQ like helicase.
    
 0.952
POLD1
DNA polymerase.
   
 0.950
DR1
Down-regulator of transcription 1.
   
 0.934
POLD2
DNA polymerase delta 2, accessory subunit.
   
 0.926
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.