STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDLBPHigh density lipoprotein binding protein. (1268 aa)    
Predicted Functional Partners:
RACK1
Receptor for activated C kinase 1.
   
 
 0.767
APOA4
Apolipoprotein A4.
     
 0.677
DDX6
DEAD-box helicase 6; Belongs to the DEAD box helicase family.
   
 
 0.643
EEF1G
Eukaryotic translation elongation factor 1 gamma.
   
 
 0.630
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]
      
 0.579
WDR31
WD repeat domain 31.
   
 
 0.565
SAE1
SUMO1 activating enzyme subunit 1.
    
 
 0.557
RPL13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
   
 
 0.519
BAX
BCL2 associated X, apoptosis regulator.
      
 0.509
KIFBP
KIF1 binding protein.
   
 
 0.490
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.