STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD276CD276 molecule. (508 aa)    
Predicted Functional Partners:
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
     
 0.784
G3UII3_LOXAF
Uncharacterized protein.
    
 
0.726
CD86
Ig-like domain-containing protein.
      
0.716
TREML2
Ig-like domain-containing protein.
   
  
 0.605
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
      
 0.579
TNFRSF9
TNF receptor superfamily member 9.
      
 0.573
TNFRSF4
TNF receptor superfamily member 4.
   
  
 0.545
CD4
CD4 molecule.
    
 0.534
ICOS
Inducible T cell costimulator.
      
 0.526
CD8A
CD8a molecule.
      
 0.519
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.