STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC6Coiled-coil domain containing 6. (451 aa)    
Predicted Functional Partners:
PPP4C
Serine/threonine-protein phosphatase.
    
 
 0.611
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
      
 0.562
MPST
Sulfurtransferase.
      
 0.534
NCOA4
Nuclear receptor coactivator 4.
      
 0.533
CCDC120
Coiled-coil domain containing 120.
      
 0.525
PDXDC1
Pyridoxal dependent decarboxylase domain containing 1.
      
 0.522
PPME1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
      
 0.518
CCDC68
Coiled-coil domain containing 68.
      
 0.515
G3SXT2_LOXAF
Uncharacterized protein.
    
 
 0.453
PPP4R1
Protein phosphatase 4 regulatory subunit 1.
    
 
 0.453
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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