node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F2 | G3TMX5_LOXAF | ENSLAFP00000008694 | ENSLAFP00000016515 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | SMB domain-containing protein. | 0.684 |
F2 | PLG | ENSLAFP00000008694 | ENSLAFP00000023609 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.894 |
F2 | SERPINC1 | ENSLAFP00000008694 | ENSLAFP00000003638 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family C member 1; Belongs to the serpin family. | 0.999 |
F2 | SERPINF1 | ENSLAFP00000008694 | ENSLAFP00000012852 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family F member 1; Belongs to the serpin family. | 0.690 |
FKBP10 | IFITM5 | ENSLAFP00000016595 | ENSLAFP00000018474 | Peptidylprolyl isomerase. | Interferon induced transmembrane protein 5. | 0.566 |
FKBP10 | SEC24D | ENSLAFP00000016595 | ENSLAFP00000001558 | Peptidylprolyl isomerase. | SEC24 homolog D, COPII coat complex component. | 0.621 |
FKBP10 | SERPINF1 | ENSLAFP00000016595 | ENSLAFP00000012852 | Peptidylprolyl isomerase. | Serpin family F member 1; Belongs to the serpin family. | 0.620 |
FKBP10 | TMEM38B | ENSLAFP00000016595 | ENSLAFP00000026244 | Peptidylprolyl isomerase. | Transmembrane protein 38B. | 0.727 |
G3TMX5_LOXAF | F2 | ENSLAFP00000016515 | ENSLAFP00000008694 | SMB domain-containing protein. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.684 |
G3TMX5_LOXAF | PLG | ENSLAFP00000016515 | ENSLAFP00000023609 | SMB domain-containing protein. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.801 |
G3TMX5_LOXAF | SERPINC1 | ENSLAFP00000016515 | ENSLAFP00000003638 | SMB domain-containing protein. | Serpin family C member 1; Belongs to the serpin family. | 0.726 |
G3TMX5_LOXAF | SERPINF1 | ENSLAFP00000016515 | ENSLAFP00000012852 | SMB domain-containing protein. | Serpin family F member 1; Belongs to the serpin family. | 0.585 |
IFITM5 | FKBP10 | ENSLAFP00000018474 | ENSLAFP00000016595 | Interferon induced transmembrane protein 5. | Peptidylprolyl isomerase. | 0.566 |
IFITM5 | SEC24D | ENSLAFP00000018474 | ENSLAFP00000001558 | Interferon induced transmembrane protein 5. | SEC24 homolog D, COPII coat complex component. | 0.532 |
IFITM5 | SERPINF1 | ENSLAFP00000018474 | ENSLAFP00000012852 | Interferon induced transmembrane protein 5. | Serpin family F member 1; Belongs to the serpin family. | 0.572 |
IFITM5 | TMEM38B | ENSLAFP00000018474 | ENSLAFP00000026244 | Interferon induced transmembrane protein 5. | Transmembrane protein 38B. | 0.588 |
LRP6 | SERPINF1 | ENSLAFP00000014083 | ENSLAFP00000012852 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Serpin family F member 1; Belongs to the serpin family. | 0.919 |
PDGFC | PLG | ENSLAFP00000010902 | ENSLAFP00000023609 | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.477 |
PDGFC | SERPINF1 | ENSLAFP00000010902 | ENSLAFP00000012852 | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. | Serpin family F member 1; Belongs to the serpin family. | 0.551 |
PLG | F2 | ENSLAFP00000023609 | ENSLAFP00000008694 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.894 |