node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APEX1 | APEX2 | ENSLAFP00000017753 | ENSLAFP00000015342 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.922 |
APEX1 | MUTYH | ENSLAFP00000017753 | ENSLAFP00000014560 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.763 |
APEX1 | NTHL1 | ENSLAFP00000017753 | ENSLAFP00000012920 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | 0.992 |
APEX1 | OGG1 | ENSLAFP00000017753 | ENSLAFP00000013805 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 8-oxoguanine DNA glycosylase. | 0.868 |
APEX2 | APEX1 | ENSLAFP00000015342 | ENSLAFP00000017753 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.922 |
APEX2 | MUTYH | ENSLAFP00000015342 | ENSLAFP00000014560 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.735 |
APEX2 | NTHL1 | ENSLAFP00000015342 | ENSLAFP00000012920 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | 0.837 |
APEX2 | OGG1 | ENSLAFP00000015342 | ENSLAFP00000013805 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 8-oxoguanine DNA glycosylase. | 0.781 |
FBH1 | MUTYH | ENSLAFP00000010972 | ENSLAFP00000014560 | F-box DNA helicase 1. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.723 |
FBH1 | NEIL3 | ENSLAFP00000010972 | ENSLAFP00000011858 | F-box DNA helicase 1. | Nei like DNA glycosylase 3. | 0.752 |
FBH1 | NTHL1 | ENSLAFP00000010972 | ENSLAFP00000012920 | F-box DNA helicase 1. | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | 0.744 |
FBH1 | NUDT15 | ENSLAFP00000010972 | ENSLAFP00000014459 | F-box DNA helicase 1. | Nudix hydrolase 15; Belongs to the Nudix hydrolase family. | 0.737 |
FBH1 | OGG1 | ENSLAFP00000010972 | ENSLAFP00000013805 | F-box DNA helicase 1. | 8-oxoguanine DNA glycosylase. | 0.603 |
GART | NTHL1 | ENSLAFP00000013687 | ENSLAFP00000012920 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | 0.790 |
GART | NUDT15 | ENSLAFP00000013687 | ENSLAFP00000014459 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Nudix hydrolase 15; Belongs to the Nudix hydrolase family. | 0.730 |
GART | UMPS | ENSLAFP00000013687 | ENSLAFP00000004307 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Uridine monophosphate synthetase. | 0.967 |
MUTYH | APEX1 | ENSLAFP00000014560 | ENSLAFP00000017753 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.763 |
MUTYH | APEX2 | ENSLAFP00000014560 | ENSLAFP00000015342 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.735 |
MUTYH | FBH1 | ENSLAFP00000014560 | ENSLAFP00000010972 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | F-box DNA helicase 1. | 0.723 |
MUTYH | NEIL3 | ENSLAFP00000014560 | ENSLAFP00000011858 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Nei like DNA glycosylase 3. | 0.793 |