STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM14PR/SET domain 14. (510 aa)    
Predicted Functional Partners:
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2.
   
 0.797
NANOG
Homeobox domain-containing protein.
    
 0.701
NANOS3
Nanos C2HC-type zinc finger 3; Belongs to the nanos family.
    
 
 0.606
JUN
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.600
LEF1
Lymphoid enhancer binding factor 1.
    
 0.599
LIN28A
Lin-28 homolog A.
   
 0.585
ESR1
NR LBD domain-containing protein.
    
 0.566
TET1
Tet methylcytosine dioxygenase 1.
      
 0.561
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.559
PRDM6
PR/SET domain 6.
    
 
0.551
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.