STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HBQ1Hemoglobin subunit theta 1; Belongs to the globin family. (142 aa)    
Predicted Functional Partners:
HBB/D
Hemoglobin subunit delta; Belongs to the globin family.
  
0.955
LOC100677792
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.778
HBG
Hemoglobin subunit gamma; Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
  
0.778
G3TGU5_LOXAF
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.752
AHSP
Alpha hemoglobin stabilizing protein.
   
 
 0.714
CYB5R4
Cytochrome b5 reductase 4.
   
 0.627
LOC100658044
Globin E1; Belongs to the globin family.
  
0.608
LOC100657757
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.607
EPB42
Erythrocyte membrane protein band 4.2.
   
  
 0.560
HBA
Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues.
  
0.557
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.