STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNFCyclin F; Belongs to the cyclin family. (781 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.888
SKP2
S-phase kinase associated protein 2.
   
 0.835
ESPL1
Extra spindle pole bodies like 1, separase.
   
  
 0.784
CCP110
Centriolar coiled-coil protein 110.
    
 
 0.773
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.762
CDC20B
Cell division cycle 20B.
   
 0.761
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.761
CDC20
Cell division cycle 20.
   
 0.761
G3U9C6_LOXAF
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.761
G3ULX5_LOXAF
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.761
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.