STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESM1Endothelial cell specific molecule 1. (184 aa)    
Predicted Functional Partners:
ID3
Inhibitor of DNA binding 3, HLH protein.
      
 0.577
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
      
 0.518
ID1
Inhibitor of DNA binding 1, HLH protein.
      
 0.510
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
      
 0.502
CALCRL
Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family.
      
 0.499
ANGPT2
Angiopoietin 2.
   
 
 0.474
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.470
G3UH47_LOXAF
Uncharacterized protein.
   
  
 0.466
MSANTD1
Myb/SANT DNA binding domain containing 1.
  
     0.465
ITGAL
Integrin subunit alpha L; Belongs to the integrin alpha chain family.
    
 0.459
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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