STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP4K3Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (896 aa)    
Predicted Functional Partners:
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
   
0.916
STK10
Uncharacterized protein.
 
 
    0.586
GRAP2
GRB2 related adaptor protein 2.
   
 
 0.526
ZBTB37
Zinc finger and BTB domain containing 37.
      
 0.524
DBNL
Drebrin like.
   
 
 0.524
IPMK
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.523
DBN1
Drebrin 1.
   
 
 0.460
ADCY4
Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
 
    
 0.443
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (30%) [HD]