node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMBP | F2 | ENSLAFP00000021495 | ENSLAFP00000008694 | Alpha-1-microglobulin/bikunin precursor. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.921 |
AMBP | FGA | ENSLAFP00000021495 | ENSLAFP00000023680 | Alpha-1-microglobulin/bikunin precursor. | Fibrinogen alpha chain. | 0.887 |
AMBP | FGB | ENSLAFP00000021495 | ENSLAFP00000014579 | Alpha-1-microglobulin/bikunin precursor. | Fibrinogen beta chain. | 0.854 |
AMBP | FGG | ENSLAFP00000021495 | ENSLAFP00000014588 | Alpha-1-microglobulin/bikunin precursor. | Fibrinogen gamma chain. | 0.832 |
AMBP | GC | ENSLAFP00000021495 | ENSLAFP00000013695 | Alpha-1-microglobulin/bikunin precursor. | GC vitamin D binding protein. | 0.796 |
AMBP | PLG | ENSLAFP00000021495 | ENSLAFP00000023609 | Alpha-1-microglobulin/bikunin precursor. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.848 |
AMBP | SERPINC1 | ENSLAFP00000021495 | ENSLAFP00000003638 | Alpha-1-microglobulin/bikunin precursor. | Serpin family C member 1; Belongs to the serpin family. | 0.883 |
AMBP | SERPIND1 | ENSLAFP00000021495 | ENSLAFP00000002279 | Alpha-1-microglobulin/bikunin precursor. | Serpin family D member 1; Belongs to the serpin family. | 0.504 |
F2 | AMBP | ENSLAFP00000008694 | ENSLAFP00000021495 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Alpha-1-microglobulin/bikunin precursor. | 0.921 |
F2 | FGA | ENSLAFP00000008694 | ENSLAFP00000023680 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen alpha chain. | 0.992 |
F2 | FGB | ENSLAFP00000008694 | ENSLAFP00000014579 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen beta chain. | 0.997 |
F2 | FGG | ENSLAFP00000008694 | ENSLAFP00000014588 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen gamma chain. | 0.997 |
F2 | GC | ENSLAFP00000008694 | ENSLAFP00000013695 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | GC vitamin D binding protein. | 0.715 |
F2 | ITGA2B | ENSLAFP00000008694 | ENSLAFP00000003562 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | 0.552 |
F2 | ITGB3 | ENSLAFP00000008694 | ENSLAFP00000011857 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Integrin beta; Belongs to the integrin beta chain family. | 0.402 |
F2 | PLG | ENSLAFP00000008694 | ENSLAFP00000023609 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.894 |
F2 | SERPINC1 | ENSLAFP00000008694 | ENSLAFP00000003638 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family C member 1; Belongs to the serpin family. | 0.999 |
F2 | SERPIND1 | ENSLAFP00000008694 | ENSLAFP00000002279 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family D member 1; Belongs to the serpin family. | 0.998 |
FGA | AMBP | ENSLAFP00000023680 | ENSLAFP00000021495 | Fibrinogen alpha chain. | Alpha-1-microglobulin/bikunin precursor. | 0.887 |
FGA | F2 | ENSLAFP00000023680 | ENSLAFP00000008694 | Fibrinogen alpha chain. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.992 |