STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MELKNon-specific serine/threonine protein kinase. (463 aa)    
Predicted Functional Partners:
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.933
DLGAP5
DLG associated protein 5.
   
  
 0.917
KIF4A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.899
NDC80
NDC80 kinetochore complex component.
   
  
 0.897
PBK
PDZ binding kinase.
   
 0.894
BIRC5
Baculoviral IAP repeat containing 5.
   
 0.878
TTK
TTK protein kinase.
   
  
 0.872
TPX2
TPX2 microtubule nucleation factor.
   
 
 0.866
BUB1B
Uncharacterized protein.
   
 
 0.861
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.858
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.