STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2064 aa)    
Predicted Functional Partners:
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
    
 0.987
AMOTL1
Angiomotin like 1.
    
 0.931
AMOTL2
Angiomotin like 2.
   
 0.926
AMOT
Angiomotin.
    
 
 0.633
HSD17B4
MaoC_dehydrat_N domain-containing protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.591
SEMA6A
Semaphorin 6A; Belongs to the semaphorin family.
   
  
 0.574
NFIB
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
   
  
 0.570
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.565
OCLN
Occludin_ELL domain-containing protein.
    
 0.544
MPP7
Membrane palmitoylated protein 7; Belongs to the MAGUK family.
    
 0.543
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.