STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTNNB1Catenin beta 1. (780 aa)    
Predicted Functional Partners:
APC
APC regulator of WNT signaling pathway.
   
 0.999
LEF1
Lymphoid enhancer binding factor 1.
    
 0.999
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
   
 0.999
CTNNBIP1
Catenin beta interacting protein 1.
    
 0.999
CREBBP
CREB binding protein.
    
 0.997
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.994
EP300
E1A binding protein p300.
    
 0.994
TCF7L2
Transcription factor 7 like 2.
    
 0.994
TCF7
Transcription factor 7.
    
 0.993
AXIN1
Axin 1.
   
 0.990
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.