STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (476 aa)    
Predicted Functional Partners:
FBP2
Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family.
   
 
 0.948
FBP1
Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.
   
 
 0.948
TIGAR
TP53 induced glycolysis regulatory phosphatase.
   
 0.948
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2.
  
 
 
0.938
PFKP
PFK domain-containing protein.
   
 0.935
PFKM
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
   
 0.935
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
   
 0.930
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
   
 0.930
HKDC1
Hexokinase domain containing 1.
   
 0.917
HK2
Hexokinase 2.
   
 0.917
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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