STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTRT3Actin related protein T3; Belongs to the actin family. (372 aa)    
Predicted Functional Partners:
DCTN2
Dynactin subunit 2.
   
 0.890
DCTN1
CAP-Gly domain-containing protein.
   
 0.860
ACTR10
Actin related protein 10; Belongs to the actin family.
   
0.851
DCTN4
Dynactin subunit 4.
   
 0.847
DCTN6
Dynactin subunit 6.
    
 0.838
DCTN5
Dynactin subunit 5.
 
 
 0.829
DCTN3
Dynactin subunit 3.
    
 0.820
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.800
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.708
ITSN2
Intersectin 2.
     
 0.689
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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