STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCAR2Cell cycle and apoptosis regulator 2. (922 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.920
RANBP3
RAN binding protein 3.
   
    0.816
EDC4
Enhancer of mRNA decapping 4.
   
    0.692
FBXO42
F-box protein 42.
   
  
 0.660
ZNF326
Zinc finger protein 326; Belongs to the AKAP95 family.
   
 
 0.620
SIRT6
Sirtuin 6.
    
 0.551
SIRT5
Sirtuin 5.
    
 0.546
HAO1
Hydroxyacid oxidase 1.
    
   0.544
CHEK2
Checkpoint kinase 2.
    
 
 0.534
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
    0.526
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.