STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (961 aa)    
Predicted Functional Partners:
SART3
Spliceosome associated factor 3, U4/U6 recycling protein.
    
 
 0.936
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.760
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
 
 
    0.750
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
 0.735
UBB
Ubiquitin B.
    
 0.635
UBC
Uncharacterized protein.
    
 0.635
USP15
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
  
 
 
0.611
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 
 0.609
SMURF2
E3 ubiquitin-protein ligase.
    
 0.608
YARS1
Tyrosine--tRNA ligase.
   
  
 0.586
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.