STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3662 aa)    
Predicted Functional Partners:
UPF1
UPF1 RNA helicase and ATPase.
   
 0.997
SMG8
SMG8 nonsense mediated mRNA decay factor.
   
 0.982
SMG9
SMG9 nonsense mediated mRNA decay factor.
    
 0.982
SMG7
SMG7 nonsense mediated mRNA decay factor.
   
 0.981
G3UN69_LOXAF
Uncharacterized protein.
   
 
 0.975
ETF1
Eukaryotic translation termination factor 1.
    
 
 0.967
EIF4A3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 0.959
GSPT2
G1 to S phase transition 2.
    
 
 0.945
RICTOR
RPTOR independent companion of MTOR complex 2.
   
 0.885
MLST8
MTOR associated protein, LST8 homolog.
    
 0.871
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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