STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1062 aa)    
Predicted Functional Partners:
VPS39
VPS39 subunit of HOPS complex.
   
 
 0.685
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
      
 0.669
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.617
SNAP29
Synaptosome associated protein 29.
      
 0.608
G3TFZ3_LOXAF
Uncharacterized protein.
    
 
 0.606
G3UE69_LOXAF
Uncharacterized protein.
    
 
 0.606
STX17
Syntaxin 17; Belongs to the syntaxin family.
      
 0.577
GABARAPL2
GABA type A receptor associated protein like 2.
    
 
 0.573
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
   
 
 0.569
CLCN7
Chloride channel protein.
      
 0.545
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.