STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLEC4EC-type lectin domain family 4 member E. (216 aa)    
Predicted Functional Partners:
SYK
Tyrosine-protein kinase.
   
 0.970
CLEC4D
C-type lectin domain family 4 member D.
   
 
0.962
FCER1G
Fc fragment of IgE receptor Ig.
   
 0.893
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.672
CLEC1A
C-type lectin domain family 1 member A.
   
 
 0.592
SF3B3
Splicing factor 3b subunit 3.
   
  
 0.591
CARD9
Caspase recruitment domain family member 9.
   
  
 0.543
CLEC1B
C-type lectin domain family 1 member B.
   
 
0.526
ICAM2
Intercellular adhesion molecule 2.
   
 
 0.436
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.417
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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