STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (722 aa)    
Predicted Functional Partners:
TBK1
TANK binding kinase 1.
  
 
0.998
TANK
TRAF family member associated NFKB activator.
   
 0.993
IRF3
IRF tryptophan pentad repeat domain-containing protein.
   
 0.992
STING1
Transmembrane protein 173.
   
 0.989
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.984
MAVS
Mitochondrial antiviral signaling protein.
    
 0.975
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.968
SIKE1
Suppressor of IKBKE 1.
     
 0.964
STAT1
Signal transducer and activator of transcription.
   
 0.951
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.945
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.