STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (651 aa)    
Predicted Functional Partners:
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
  
 0.934
KL
Klotho.
    
 0.917
AKR1A1
Aldo-keto reductase family 1 member A1.
   
 
 0.913
SPAM1
Uncharacterized protein.
    
 0.912
HYAL2
Hyaluronidase.
    
 0.912
HYAL4
Hyaluronidase.
    
 0.912
CES1
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.907
CES2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.907
LOC100674078
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.907
G3UGH4_LOXAF
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.907
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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