STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF4Rho guanine nucleotide exchange factor 4. (489 aa)    
Predicted Functional Partners:
APC
APC regulator of WNT signaling pathway.
   
 0.992
RAC2
Rac family small GTPase 2.
    
 0.948
SPATA13
Uncharacterized protein.
  
 
 
0.907
CDC42
Uncharacterized protein.
    
 0.763
APC2
APC regulator of WNT signaling pathway 2.
   
 
 0.695
KHDRBS2
KH RNA binding domain containing, signal transduction associated 2.
   
  
 0.596
CDHR5
Cadherin related family member 5.
   
  
 0.589
MAPRE3
Microtubule associated protein RP/EB family member 3.
      
 0.558
LGSN
Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family.
   
  
 0.532
PTPN18
Protein tyrosine phosphatase non-receptor type 18.
      
 0.527
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.