STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1010 aa)    
Predicted Functional Partners:
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.995
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.992
ATF4
Activating transcription factor 4.
     
 0.969
EIF2AK4
Eukaryotic translation initiation factor 2 alpha kinase 4.
   
 
0.950
NFE2L2
Nuclear factor, erythroid 2 like 2.
   
 0.932
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.913
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.913
G3T1E4_LOXAF
Uncharacterized protein.
   
 0.910
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
 0.910
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
   
 
 0.906
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.