node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ETS1 | ETS2 | ENSLAFP00000023695 | ENSLAFP00000003727 | ETS proto-oncogene 1, transcription factor. | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | 0.699 |
ETS1 | PAX8 | ENSLAFP00000023695 | ENSLAFP00000017751 | ETS proto-oncogene 1, transcription factor. | Paired domain-containing protein. | 0.551 |
ETS2 | ETS1 | ENSLAFP00000003727 | ENSLAFP00000023695 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | ETS proto-oncogene 1, transcription factor. | 0.699 |
ETS2 | PAX8 | ENSLAFP00000003727 | ENSLAFP00000017751 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | Paired domain-containing protein. | 0.551 |
PAX8 | ETS1 | ENSLAFP00000017751 | ENSLAFP00000023695 | Paired domain-containing protein. | ETS proto-oncogene 1, transcription factor. | 0.551 |
PAX8 | ETS2 | ENSLAFP00000017751 | ENSLAFP00000003727 | Paired domain-containing protein. | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | 0.551 |
PAX8 | PPARG | ENSLAFP00000017751 | ENSLAFP00000024076 | Paired domain-containing protein. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.964 |
PAX8 | PRKACA | ENSLAFP00000017751 | ENSLAFP00000020656 | Paired domain-containing protein. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.904 |
PAX8 | PRKACB | ENSLAFP00000017751 | ENSLAFP00000005492 | Paired domain-containing protein. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.904 |
PAX8 | PRKCA | ENSLAFP00000017751 | ENSLAFP00000004849 | Paired domain-containing protein. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.904 |
PAX8 | PRKCB | ENSLAFP00000017751 | ENSLAFP00000000867 | Paired domain-containing protein. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.904 |
PAX8 | PRKCG | ENSLAFP00000017751 | ENSLAFP00000021510 | Paired domain-containing protein. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.904 |
PAX8 | RXRG | ENSLAFP00000017751 | ENSLAFP00000006754 | Paired domain-containing protein. | Retinoid X receptor gamma. | 0.902 |
PAX8 | TSHR | ENSLAFP00000017751 | ENSLAFP00000000922 | Paired domain-containing protein. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.575 |
PPARG | PAX8 | ENSLAFP00000024076 | ENSLAFP00000017751 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Paired domain-containing protein. | 0.964 |
PPARG | RXRG | ENSLAFP00000024076 | ENSLAFP00000006754 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Retinoid X receptor gamma. | 0.987 |
PRKACA | PAX8 | ENSLAFP00000020656 | ENSLAFP00000017751 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | Paired domain-containing protein. | 0.904 |
PRKACA | PRKACB | ENSLAFP00000020656 | ENSLAFP00000005492 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.900 |
PRKACB | PAX8 | ENSLAFP00000005492 | ENSLAFP00000017751 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Paired domain-containing protein. | 0.904 |
PRKACB | PRKACA | ENSLAFP00000005492 | ENSLAFP00000020656 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.900 |