STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100670379Histone H2A; Belongs to the histone H2A family. (130 aa)    
Predicted Functional Partners:
LOC100657920
Histone H2B; Belongs to the histone H2B family.
 
 0.947
H2BC5
Histone H2B; Belongs to the histone H2B family.
 
 0.947
H2BC3
Histone H2B; Belongs to the histone H2B family.
 
 0.947
LOC100661012
Histone H2B; Belongs to the histone H2B family.
 
 
 0.936
LOC111752376
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.936
LOC100669973
Histone H2B; Belongs to the histone H2B family.
 
 
 0.936
ENSLAFP00000016306
annotation not available
   
 0.936
ENSLAFP00000018530
annotation not available
   
 0.936
H4C11
H4 clustered histone 11.
   
 0.936
LOC100660148
Histone H2B; Belongs to the histone H2B family.
 
 
 0.936
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.