STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZER1Zyg-11 related cell cycle regulator. (758 aa)    
Predicted Functional Partners:
CUL2
Cullin 2; Belongs to the cullin family.
    
 0.870
VHL
Uncharacterized protein.
   
 
 0.720
ELOC
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 
 0.632
ELOB
Elongin B.
    
 0.625
RBX1
Ring-box 1.
     
 0.578
LRR1
Leucine rich repeat protein 1.
      
 0.575
ZYG11B
Zyg-11 family member B, cell cycle regulator.
     
0.530
PPTC7
Protein phosphatase; Belongs to the PP2C family.
      
 0.530
SNX11
Sorting nexin 11.
      
 0.514
FPGS
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
      
 0.457
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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