STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3TSP6_LOXAFGlyco_18 domain-containing protein. (387 aa)    
Predicted Functional Partners:
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
     
 0.744
G3TC70_LOXAF
Uncharacterized protein.
    
 
 0.666
SLC35B4
Solute carrier family 35 member B4.
      
 0.614
SFTPB
Surfactant protein B.
     
 0.579
ENKUR
Enkurin, TRPC channel interacting protein.
    
 
 0.543
EFHC1
EF-hand domain containing 1.
    
 
 0.534
EFHC2
EF-hand domain containing 2.
    
 
 0.534
SLC35A3
Solute carrier family 35 member A3.
   
  
 0.524
TIMM21
Translocase of inner mitochondrial membrane 21.
      
 0.521
COPE
Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.
   
    0.501
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.