STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLK1Delta like non-canonical Notch ligand 1. (355 aa)    
Predicted Functional Partners:
IGF2
Insulin like growth factor 2.
   
 
 0.748
RTL1
RT_RNaseH_2 domain-containing protein.
    
 0.602
CPA4
Carboxypeptidase A4.
    
 
 0.577
NOTCH1
Uncharacterized protein.
     
0.576
DIO3
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.573
SLC22A18
Solute carrier family 22 member 18.
    
 
 0.557
FOSL1
FOS like 1, AP-1 transcription factor subunit.
    
 
 0.552
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 
 0.539
GRB10
Growth factor receptor bound protein 10.
   
 0.535
IGF2R
Insulin like growth factor 2 receptor.
    
 
 0.505
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.