STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (367 aa)    
Predicted Functional Partners:
G3UG48_LOXAF
Uncharacterized protein.
    
 
 0.957
KDM8
Lysine demethylase 8.
      
 0.576
BRD2
Bromodomain containing 2.
    
 
 0.563
BRD3
Bromodomain containing 3.
    
 
 0.525
KDM5A
Lysine demethylase 5A.
      
 0.524
BRDT
Uncharacterized protein.
    
 
 0.522
GULP1
GULP PTB domain containing engulfment adaptor 1.
      
 0.521
G3UH36_LOXAF
Bromo domain-containing protein.
    
 
 0.487
G3U8T3_LOXAF
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.470
ENSLAFP00000028190
annotation not available
    
 0.470
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.