STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIAA2013KIAA2013. (627 aa)    
Predicted Functional Partners:
VPS13D
Vacuolar protein sorting 13 homolog D.
      
 0.588
OTUD4
OTU deubiquitinase 4.
   
  
 0.539
MBLAC2
Metallo-beta-lactamase domain containing 2.
      
 0.527
ATP6AP1
ATPase H+ transporting accessory protein 1.
    
   0.483
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
   
  
 0.483
ESYT2
Extended synaptotagmin 2.
      
 0.480
HECTD3
HECT domain E3 ubiquitin protein ligase 3.
      
 0.450
NSUN6
NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.442
GET3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
      
 0.441
PDXDC1
Pyridoxal dependent decarboxylase domain containing 1.
      
 0.439
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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