STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOM1L2Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family. (493 aa)    
Predicted Functional Partners:
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.716
TOLLIP
Toll interacting protein.
    
 
 0.667
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.659
RABGEF1
Uncharacterized protein.
   
 
 0.619
UEVLD
UEV and lactate/malate dehyrogenase domains.
   
 
 0.567
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.519
MST1R
Macrophage stimulating 1 receptor.
    
  0.518
IGF2R
Insulin like growth factor 2 receptor.
    
 
 0.493
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
   0.485
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
    
 0.484
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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