STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORCS2Sortilin. (357 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
     
 0.949
G3UAF1_LOXAF
Uncharacterized protein.
 
      0.900
NGF
Nerve growth factor; Belongs to the NGF-beta family.
    
 
 0.730
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
      
 0.622
SORT1
Sortilin.
    
 
0.566
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
     
 0.559
NGFR
Nerve growth factor receptor.
    
 
 0.527
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.516
CLTC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.502
IGF2R
Insulin like growth factor 2 receptor.
    
 0.502
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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