STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRM4Glutamate metabotropic receptor 4. (914 aa)    
Predicted Functional Partners:
GRM6
Glutamate metabotropic receptor 6.
  
  
 
0.901
GRM8
G_PROTEIN_RECEP_F3_4 domain-containing protein.
  
  
 
0.900
GNA13
G protein subunit alpha 13.
    
  0.708
GNA12
G protein subunit alpha 12.
    
  0.708
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
  0.673
AGT
Angiotensinogen; Belongs to the serpin family.
   
 
  0.669
AVP
Neurophysin 2; Neurophysin 2 specifically binds vasopressin; Belongs to the vasopressin/oxytocin family.
   
 
  0.659
G3UF61_LOXAF
Uncharacterized protein.
     
 0.657
LOC100669226
Uncharacterized protein.
   
 
  0.651
CXCL8
Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.
     
  0.650
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.