STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBM4RNA binding motif protein 4. (365 aa)    
Predicted Functional Partners:
EIF4E2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.725
EPAS1
Endothelial PAS domain protein 1.
   
 
 0.720
G3TJM4_LOXAF
Uncharacterized protein.
   
 0.665
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.531
G3TRE8_LOXAF
Ubiquitin-like domain-containing protein.
   
 0.531
NOL8
Nucleolar protein 8.
     
 0.523
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 
 0.502
NCBP1
Nuclear cap binding protein subunit 1.
    
 0.486
SRSF2
RRM domain-containing protein.
    
 0.481
EIF4E
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
    
 0.446
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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