STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNDC2Thioredoxin; Belongs to the thioredoxin family. (105 aa)    
Predicted Functional Partners:
TXNIP
Thioredoxin interacting protein.
    
 0.990
TXN2
Thioredoxin 2.
  
0.959
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.884
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.838
MSRA
PMSR domain-containing protein.
  
 0.824
TXNRD2
Thioredoxin reductase 2.
   
 0.805
TXNRD3
Thioredoxin reductase 3.
   
 0.741
TXNRD1
Thioredoxin reductase 1.
   
 0.741
PRDX6
Peroxiredoxin 6.
  
 0.732
MAP3K6
Mitogen-activated protein kinase kinase kinase 6.
    
 0.708
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.