STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRASKRAS proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.808
G3U095_LOXAF
Uncharacterized protein.
   
 0.808
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.795
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.772
RASA1
RAS p21 protein activator 1.
   
 0.743
NF1
Neurofibromin 1.
   
 0.735
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.699
ITSN1
Intersectin 1.
    
 0.692
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.691
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 0.689
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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