STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)    
Predicted Functional Partners:
FGFR4
Fibroblast growth factor receptor.
    
 0.840
FGFR3
Fibroblast growth factor receptor.
    
 0.797
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
    
 
 0.731
G3TWY0_LOXAF
Uncharacterized protein.
     
 0.721
FGFR1
Fibroblast growth factor receptor.
    
 0.720
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
   
 
0.704
FGFR2
Fibroblast growth factor receptor.
    
 0.692
FGFRL1
Fibroblast growth factor receptor like 1.
    
 0.662
G3SMI1_LOXAF
Uncharacterized protein.
    
 0.646
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
  
  
0.645
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (22%) [HD]