STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (794 aa)    
Predicted Functional Partners:
LRRC8A
Leucine rich repeat containing 8 VRAC subunit A.
  
 
0.899
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
    
   0.658
ADGRL2
Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.
    
   0.658
ADGRL1
Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.
    
   0.658
TTYH3
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.541
LRRC8B
Leucine rich repeat containing 8 VRAC subunit B.
  
 
0.539
TTC8
Tetratricopeptide repeat domain 8.
    
 
 0.533
KERA
Keratocan.
  
     0.527
DCN
Decorin; May affect the rate of fibrils formation.
  
     0.522
RABEPK
Rab9 effector protein with kelch motifs.
    
 
 0.522
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.