node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASPH | F10 | ENSLAFP00000011119 | ENSLAFP00000020209 | Aspartate beta-hydroxylase. | Coagulation factor X. | 0.693 |
F10 | ASPH | ENSLAFP00000020209 | ENSLAFP00000011119 | Coagulation factor X. | Aspartate beta-hydroxylase. | 0.693 |
F10 | F2 | ENSLAFP00000020209 | ENSLAFP00000008694 | Coagulation factor X. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.977 |
F10 | F3 | ENSLAFP00000020209 | ENSLAFP00000010371 | Coagulation factor X. | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | 0.906 |
F10 | F5 | ENSLAFP00000020209 | ENSLAFP00000001652 | Coagulation factor X. | Coagulation factor V; Belongs to the multicopper oxidase family. | 0.942 |
F10 | F7 | ENSLAFP00000020209 | ENSLAFP00000005004 | Coagulation factor X. | Uncharacterized protein. | 0.978 |
F10 | F8 | ENSLAFP00000020209 | ENSLAFP00000012801 | Coagulation factor X. | Coagulation factor VIII; Belongs to the multicopper oxidase family. | 0.882 |
F10 | F9 | ENSLAFP00000020209 | ENSLAFP00000004944 | Coagulation factor X. | Coagulation factor IX. | 0.932 |
F10 | SERPINC1 | ENSLAFP00000020209 | ENSLAFP00000003638 | Coagulation factor X. | Serpin family C member 1; Belongs to the serpin family. | 0.992 |
F10 | TFPI | ENSLAFP00000020209 | ENSLAFP00000014265 | Coagulation factor X. | Tissue factor pathway inhibitor. | 0.853 |
F10 | VWF | ENSLAFP00000020209 | ENSLAFP00000001947 | Coagulation factor X. | Von Willebrand factor. | 0.942 |
F2 | F10 | ENSLAFP00000008694 | ENSLAFP00000020209 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor X. | 0.977 |
F2 | F3 | ENSLAFP00000008694 | ENSLAFP00000010371 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | 0.784 |
F2 | F5 | ENSLAFP00000008694 | ENSLAFP00000001652 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor V; Belongs to the multicopper oxidase family. | 0.996 |
F2 | F7 | ENSLAFP00000008694 | ENSLAFP00000005004 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.788 |
F2 | F8 | ENSLAFP00000008694 | ENSLAFP00000012801 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor VIII; Belongs to the multicopper oxidase family. | 0.907 |
F2 | F9 | ENSLAFP00000008694 | ENSLAFP00000004944 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor IX. | 0.723 |
F2 | SERPINC1 | ENSLAFP00000008694 | ENSLAFP00000003638 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family C member 1; Belongs to the serpin family. | 0.999 |
F2 | TFPI | ENSLAFP00000008694 | ENSLAFP00000014265 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Tissue factor pathway inhibitor. | 0.692 |
F2 | VWF | ENSLAFP00000008694 | ENSLAFP00000001947 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Von Willebrand factor. | 0.721 |