STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (846 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.965
PDS5A
PDS5 cohesin associated factor A.
   
 0.891
WAPL
WAPL cohesin release factor.
   
 
 0.809
PDS5B
PDS5 cohesin associated factor B.
   
 0.804
SMC4
Structural maintenance of chromosomes protein.
   
 0.799
SMC5
SMC_N domain-containing protein.
   
 0.783
SMC2
Structural maintenance of chromosomes protein.
   
 0.779
SMC1B
Structural maintenance of chromosomes protein.
   
 0.769
SMC1A
Structural maintenance of chromosomes protein.
   
 0.769
STAG1
Stromal antigen 1.
   
 0.753
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.