STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKCRK proto-oncogene, adaptor protein. (307 aa)    
Predicted Functional Partners:
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.997
CBL
Cbl proto-oncogene.
    
 0.995
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.983
ELMO2
Engulfment and cell motility 2.
    
 0.982
FRS2
Fibroblast growth factor receptor substrate 2.
   
 0.981
ELMO1
Engulfment and cell motility 1.
    
 0.980
GAB1
GRB2 associated binding protein 1.
    
 0.978
SRC
Tyrosine-protein kinase.
   
 0.977
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
    
 0.976
EGFR
Receptor protein-tyrosine kinase.
    
 0.976
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.