STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K11Mitogen-activated protein kinase kinase kinase 11. (781 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
   
 0.971
MAP2K7
Mitogen-activated protein kinase kinase 7.
  
0.952
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 0.952
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 0.943
MAPK8IP3
Mitogen-activated protein kinase 8 interacting protein 3.
   
 0.928
MAP4K1
Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
   
0.915
EXOSC9
Exosome component 9.
   
 
 0.610
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.588
MRPL30
Ribosomal_L30 domain-containing protein.
      
 0.581
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.577
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.