STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRMD8FERM domain containing 8. (454 aa)    
Predicted Functional Partners:
ITGB1BP1
Integrin subunit beta 1 binding protein 1.
    
 
 0.727
SEC22B
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
      
 0.553
ZNRD2
Zinc ribbon domain containing 2.
      
 0.520
PDCD10
Programmed cell death 10.
    
 
 0.503
SLC25A45
Solute carrier family 25 member 45; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.502
C12orf43
Chromosome 12 open reading frame 43.
   
    0.483
CCDC60
Coiled-coil domain containing 60.
      
 0.453
FAM89B
Family with sequence similarity 89 member B.
      
 0.449
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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