STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (379 aa)    
Predicted Functional Partners:
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
  
 0.611
ASCC2
Activating signal cointegrator 1 complex subunit 2.
      
 0.601
DGCR2
DiGeorge syndrome critical region gene 2.
      
 0.591
KANSL2
KAT8 regulatory NSL complex subunit 2.
   
  
 0.590
PRCC
Proline rich mitotic checkpoint control factor.
   
  
 0.565
PRPF19
Pre-mRNA processing factor 19.
   
  
 0.563
ZNF830
Zinc finger protein 830.
      
 0.562
XAB2
XPA binding protein 2.
      
 0.543
SNW1
SNW domain containing 1.
      
 0.519
MED15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.517
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.