STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3U399_LOXAFUncharacterized protein. (40 aa)    
Predicted Functional Partners:
AGRN
Agrin.
    
 0.635
DKK1
Dickkopf-like protein 1.
    
 0.608
ITSN2
Intersectin 2.
    
 0.604
G3U095_LOXAF
Uncharacterized protein.
    
 0.604
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
    
 0.578
RELN
Reelin.
    
 0.577
KREMEN1
Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.
   
 0.550
PCSK9
Proprotein convertase subtilisin/kexin type 9.
    
 0.541
HSPG2
Heparan sulfate proteoglycan 2.
   
 0.536
DAB2
DAB adaptor protein 2.
    
 0.527
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.